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Hideki Wanibuchi Selected Research

Diethylnitrosamine (N-Nitrosodiethylamine)

7/2021Canopy Homolog 2 as a Novel Molecular Target in Hepatocarcinogenesis.
8/2017Enhanced Susceptibility of Ogg1 Mutant Mice to Multiorgan Carcinogenesis.
1/2017Diphenylarsinic acid exerts promotion effects on hepatobiliary carcinogenesis in a rat medium-term multiorgan carcinogenicity bioassay.
1/2017A carcinogenicity study of diphenylarsinic acid in F344 rats in drinking water for 104 weeks.
11/2013Diphenylarsinic acid, a chemical warfare-related neurotoxicant, promotes liver carcinogenesis via activation of aryl hydrocarbon receptor signaling and consequent induction of oxidative DNA damage in rats.
1/2011Mitochondrial prohibitins and septin 9 are implicated in the onset of rat hepatocarcinogenesis.
1/2010Cytokeratin 8/18 as a new marker of mouse liver preneoplastic lesions.
12/2009Characteristic upregulation of glucose-regulated protein 78 in an early lesion negative for hitherto established cytochemical markers in rat hepatocarcinogenesis.
7/2009Cytokeratin 8/18 overexpression and complex formation as an indicator of GST-P positive foci transformation into hepatocellular carcinomas.
1/2009Enhancement of preneoplastic lesion yield by Chios Mastic Gum in a rat liver medium-term carcinogenesis bioassay.
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Hideki Wanibuchi Research Topics

Disease

72Neoplasms (Cancer)
08/2022 - 01/2002
58Carcinogenesis
08/2022 - 01/2002
16Carcinoma (Carcinomatosis)
07/2021 - 01/2003
16Body Weight (Weight, Body)
12/2018 - 05/2002
14Urinary Bladder Neoplasms (Bladder Cancer)
01/2021 - 01/2000
14Hyperplasia
01/2021 - 01/2002
8Adenocarcinoma
10/2017 - 01/2002
7Hepatocellular Carcinoma (Hepatoma)
10/2020 - 04/2007
6Adenoma (Adenomas)
07/2021 - 01/2002
6Cystitis
11/2009 - 04/2003
5Inflammation (Inflammations)
01/2022 - 11/2009
5Fibrosis (Cirrhosis)
10/2020 - 01/2005
5Squamous Cell Carcinoma (Epidermoid Carcinoma)
02/2016 - 08/2008
5Liver Cell Adenoma (Hepatocellular Adenoma)
01/2010 - 01/2006
4Liver Neoplasms (Liver Cancer)
07/2021 - 07/2002
4Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2017 - 08/2003
4Colonic Neoplasms (Colon Cancer)
03/2009 - 01/2002
4Aberrant Crypt Foci
01/2005 - 09/2002
3Neoplasm Metastasis (Metastasis)
02/2017 - 03/2013
3Papilloma (Papillomatosis)
12/2013 - 08/2002
3Pancreatic Neoplasms (Pancreatic Cancer)
08/2013 - 03/2011
3Diabetic Nephropathies (Diabetic Nephropathy)
05/2012 - 01/2011
2Necrosis
01/2022 - 02/2010
2Diabetes Mellitus
03/2021 - 01/2007
2Type 2 Diabetes Mellitus (MODY)
10/2020 - 03/2011
2Metabolic Syndrome (Dysmetabolic Syndrome X)
10/2020 - 11/2018
2Non-alcoholic Fatty Liver Disease
10/2020 - 02/2017
2Alcoholic Fatty Liver
10/2020 - 02/2017
2Starvation
10/2019 - 06/2014
2Infections
01/2019 - 08/2008
2Hypoxia (Hypoxemia)
04/2018 - 03/2014
2Lung Neoplasms (Lung Cancer)
01/2017 - 08/2004
2Tetraploidy
06/2014 - 08/2004

Drug/Important Bio-Agent (IBA)

22Proteins (Proteins, Gene)FDA Link
07/2021 - 08/2003
22CarcinogensIBA
01/2017 - 01/2000
14Biomarkers (Surrogate Marker)IBA
03/2021 - 03/2009
13Diethylnitrosamine (N-Nitrosodiethylamine)IBA
07/2021 - 01/2006
10Glutathione Transferase (Glutathione S-Transferase)IBA
10/2018 - 08/2003
9Drinking WaterIBA
01/2020 - 08/2004
88-Hydroxy-2'-DeoxyguanosineIBA
10/2020 - 02/2002
8Cacodylic Acid (Cacodylate)IBA
01/2020 - 01/2002
7ProteomeIBA
11/2018 - 07/2009
7Messenger RNA (mRNA)IBA
02/2015 - 08/2003
7ArsenicIBA
01/2007 - 01/2002
61,2-Dimethylhydrazine (1,2 Dimethylhydrazine)IBA
08/2017 - 12/2003
6Ethanol (Ethyl Alcohol)IBA
03/2017 - 09/2002
5EnzymesIBA
10/2019 - 11/2005
5Dimenhydrinate (DMH)FDA LinkGeneric
08/2017 - 12/2003
5DNA (Deoxyribonucleic Acid)IBA
08/2017 - 08/2004
5Phenobarbital (Luminal)FDA Link
01/2017 - 02/2002
5ErbB Receptors (EGF Receptor)IBA
02/2016 - 08/2003
5Proliferating Cell Nuclear Antigen (PCNA)IBA
04/2006 - 03/2002
4ButylhydroxybutylnitrosamineIBA
08/2022 - 12/2003
4Pharmaceutical PreparationsIBA
06/2022 - 01/2006
4LipidsIBA
01/2022 - 03/2014
4Cyclin D1IBA
07/2021 - 08/2002
4NitrosaminesIBA
08/2017 - 03/2004
4ParaffinIBA
02/2017 - 04/2004
4diphenylarsinic acidIBA
01/2017 - 11/2007
4Thioacetamide (Thioacetamid)IBA
05/2008 - 01/2005
3Small Interfering RNA (siRNA)IBA
03/2021 - 03/2011
3Cadherins (E-Cadherin)IBA
12/2018 - 01/2006
3Propolis (Bee Bread)IBA
03/2017 - 09/2015
3Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
03/2017 - 01/2006
3NF-kappa B (NF-kB)IBA
03/2017 - 04/2003
3Indicators and Reagents (Reagents)IBA
05/2016 - 07/2009
3CytokinesIBA
01/2016 - 05/2002
3Biological ProductsIBA
08/2015 - 12/2003
3AzoxymethaneIBA
01/2007 - 07/2004
3Transforming Growth Factor alpha (TGF-alpha)IBA
06/2006 - 01/2004
3beta CateninIBA
01/2006 - 09/2005
3Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
01/2005 - 12/2003
34- (4- cyclohexyl- 2- methyloxazol- 5- yl)- 2- fluorobenzenesulfonamideIBA
01/2005 - 12/2003
3monomethylarsonic acid (MSMA)IBA
08/2004 - 07/2002
2CateninsIBA
08/2022 - 02/2017
2Immune Checkpoint InhibitorsIBA
06/2022 - 01/2020
2SeptinsIBA
07/2021 - 04/2010
2Polysaccharides (Glycans)IBA
10/2020 - 01/2016
2Glucose (Dextrose)FDA LinkGeneric
10/2020 - 12/2009
2Histones (Histone)IBA
01/2020 - 07/2009
2AntibodiesIBA
01/2020 - 03/2011
2AminesIBA
12/2019 - 06/2006
2diisopropanolnitrosamineIBA
08/2017 - 01/2002
2Methylnitrosourea (N-Methyl-N-nitrosourea)IBA
08/2017 - 01/2017
2Dextrans (Dextran)FDA Link
03/2017 - 01/2016
2sodium sulfate (sodium bisulfate)FDA LinkGeneric
03/2017 - 01/2016
2Formaldehyde (Formol)FDA Link
02/2017 - 05/2012
2ENNGIBA
11/2016 - 03/2012
2Estrogens (Estrogen)FDA Link
11/2016 - 05/2005
2N-nitroso-tris-chloroethylureaIBA
02/2016 - 12/2013
2AntioxidantsIBA
01/2016 - 06/2010
2propylene dichlorideIBA
05/2015 - 01/2015
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2015 - 01/2007
2AntigensIBA
01/2015 - 03/2011
2ethyl tert-butyl ether (ETBE)IBA
01/2015 - 12/2013

Therapy/Procedure

6Therapeutics
01/2020 - 03/2004
4Lasers (Laser)
01/2015 - 07/2009
4Chemoprevention
01/2007 - 01/2000
3Oral Administration
01/2016 - 01/2002
2Immunotherapy
06/2022 - 12/2016